#unburdenYourhealth with us

Common patterns of Secondary Dyslipidemias

  • May 18,2021
  • 5 Min Read
Common patterns of Secondary Dyslipidemias

Disease Factor

TG

HDL-C

LDL-C

Acromegaly

Alcoholism

↑↑

Anorexia nervosa

↔/↑

Chronic renal failure

Cigarette smoking

Diabetes mellitus

Drugs

Antiviral medications (HIV protease inhibitors)

Beta blockers

↔/↑

Cyclosporine

Exogenous estrogens

Glucocorticoids

↑/↔

↑/↔

Retinoic acid derivatives

Thiazide diuretics

↔/↑

Hypothyroidism

↔/↑

↓/↔/↑*

Lipodystrophy

Nephrotic syndrome

↔/↑

Obstructive liver disease**

↑↑**

 

TG- Triglycerides; HDL-C-High Density Lipoprotein Cholesterol; LDL-C - Low Density Lipoprotein Cholesterol

*High, normal, or low values have been reported in different series

**Unusual lipoprotein particles, such as lipoprotein-X, may accumulate and levels of high-density lipoprotein cholesterol are typically elevated.

***HDL levels tend to decrease in the later stages of the disease

 

References:

  1. Williamson MA, Snyder LM, editors. Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis. 10th edition. Philadelphia: Wolters Kluwer Health; 2015. 1390 p.
  2. Keskin H, Cadirci K, Kaye Y, Durmaz S, Arslan A, Yildiz F, et al. Acromegaly and Dyslipidemia. Endocr Abstr [Internet]. 2016 May 13 [cited 2020 Aug 3]; Available from: http://www.endocrine-    abstracts.org/ea/0041/ea0041EP708.htm
  3. Chowdhury I. Alcohol and Dyslipidemia. In: Watson RR, Preedy VR, Zibadi S, editors. Alcohol, Nutrition, and Health Consequences [Internet]. Totowa, NJ: Humana Press; 2013 [cited 2020 Aug 4]. p. 329-39. Available from: http:filink.springe.com/10.1007/978-1-62703-047-2_26
  4. Kockx M, Kritharides L. Cyclosporin A-Induced Hyperlipidemia. In: Kostner G, editor. Lipoproteins - Role in Health and Diseases [Internet]. InTech; 2012 [cited 2020 Aug 4]. Available from:     http://www.intechopen.com/books/lipoproteins-role-in-health-and-diseases/cyclosporin-a-induced-hyperlipidemia
  5. Ohwada R, Hotta M, Oikawa S, Takano K. Etiology of hypercholesterolemia in patients with anorexia nervosa. Int J Eat Disord. 2006 Nov;39(7):598-601.
  6. Jauregui-Garrigo B, Bolanos-Rios P, Santiago-Fernandez MJ, Jauregui-Lobera I. Lipid profile and cardiovascular risk in anorexia nervosa; the effect of nutritional treatment. Nutr Hosp. 2012
  7. May1; (3):908-13.        
  8. Duarte JD, Cooper-DeHoff RM. Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther. 2010 Jun;8(6):793-802.
  9. Agdeppa D, Macaron C, Mallik T, Schnuda ND. Plasma high density lipoprotein cholesterol in thyroid disease. J Clin Endocrinol Metab. 1979 Nov;49(5):726-9.
  10. Muls E, Rosseneu M, Blaton V, Lesaffre E, Lamberigts G, de Moor P Serum lipids and apolipoproteins A-I, A-II and B in primary hypothyroidism before and during treatment. EurJ Clin Invest. 1984 Feb;14(1):12-5.
 

Leave a reply

Most Viewed

Premarital Screening

Typhoid

Dengue

Home Quarantine Tips

Vitamin D and Diabetes

Cervical Cancer Screening

COVID-19 Symptoms